Fostamatinib
Cat. No.:YN440245
产品名称: | Fostamatinib |
CAS No.: | 901119-35-5 |
Chemical Name: | R 788; 6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one |
Synonyms: | 福他替尼; R788 |
分子量: | 580.46 |
分子式: | C₂₃H₂₆FN₆O₉P |
SMILES: | COC1=CC(NC2=NC=C(C(NC3=NC(N4COP(O)(O)=O)=C(C=C3)OC(C)(C)C4=O)=N2)F)=CC(OC)=C1OC |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Fostamatinib (R788) 是R406的活性代谢物的原药,是Syk抑制剂,IC50为41 nM。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Calvayrac, O., et.al.: PCT Int. Appl., 47, (2021)