Piceatannol
Cat. No.：YN440275
CAS No. ：10083-24-6
规格
价格(RMB)
库存
| 产品名称: | Piceatannol |
| CAS No.: | 10083-24-6 |
| Chemical Name: | 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-1,2-benzenediol |
| Synonyms: | 白皮杉醇; Astringenin; trans |
| 分子量: | 244.24 |
| 分子式: | C₁₄H₁₂O₄ |
| SMILES: | OC1=CC=C(/C=C/C2=CC(O)=CC(O)=C2)C=C1O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Piceatannol是蛋白质酪氨酸激酶Syk的选择性抑制剂，它能够抑制ICa,L, Ito, IKr，Ca2+转移和除了IK1的Na+-Ca2+交换。 |
| IC50和靶点: | |
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Potter, G.A., Patterson, L.H., Wanogho, E., et al.The cancer preventative agent resveratrol is converted to the anticancer agent piceatannol by the cytochrome P450 enzyme CYPIBIBr. J. Cancer86(5),774-778(2002)
Rotondo, S., Rajtar, G., Manarini, S., et al.Effect of trans-resveratrol, a natural polyphenolic compound, on human polymorphonuclear leukocyte functionBr. J. Pharmacol.123(8),1691-1699(1998)
Wieder, T., Prokop, A., Bagci, B., et al.Piceatannol, a hydroxylated analog of the chemopreventive agent resveratrol, is a potent inducer of apoptosis in the lymphoma cell line BJAB and in primary, leukemic lymphoblastsLeukemia15(11),1735-1742(2001)
Lin, W.-S., Chueh, T.-L., Nagabhushanam, K., et al.Piceatannol and 3'-hydroxypterostilbene alleviate inflammatory bowel disease by maintaining intestinal epithelial integrity and regulating gut microbiota in miceJ. Agric. Food Chem.71(4),1994-2005(2023)
