R112
Cat. No.:YN440361
产品名称: | R112 |
CAS No.: | 575474-82-7 |
Chemical Name: | 3,3'-[(5-fluoro-2,4-pyrimidinediyl)diimino]bis-phenol |
Synonyms: | (E)-Elafibranor |
分子量: | 312.30 |
分子式: | C₁₆H₁₃FN₄O₂ |
SMILES: | FC1=CN=C(NC2=CC(O)=CC=C2)N=C1NC3=CC(O)=CC=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | R112是一种ATP竞争性的Syk激酶抑制剂, Ki值为6 nM. R112抑制Syk激酶活性, IC50值为226 nM。 |
IC50和靶点: | |
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Rossi, A.B., Herlaar, E., Braselmann, S., et al.Identification of the Syk kinase inhibitor R112 by a human mast cell screenJ. Allergy Clin. Immunol.118(3),749-755(2006)