Risdiplam
Cat. No.：YN290089
CAS No. ：1825352-65-5
| 产品名称: | Risdiplam |
| CAS No.: | 1825352-65-5 |
| Chemical Name: | 7-(4,7-diazaspiro[2.5]oct-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-4H-pyrido[1,2-a]pyrimidin-4-one |
| Synonyms: | RG7916; RO7034067 |
| 分子量: | 401.46 |
| 分子式: | C₂₂H₂₃N₇O |
| SMILES: | O=C(C=C(C(C=C1C)=NN2C1=NC(C)=C2)N=C3C=C4)N3C=C4N(CCN5)CC65CC6 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Risdiplam (RG7916) 是一种运动神经元存活基因SMN2的前体 mRNA 剪接修饰剂，可增加SMN蛋白水平。 |
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Ratni, H., Ebeling, M., Baird, J., et al.Discovery of risdiplam, a selective survival of motor neuron-2 (SMN2) gene splicing modifier for the treatment of spinal muscular atrophy (SMA)J. Med. Chem.61(15),6501-6517(2018)
