BMH-21
Cat. No.：YN290205
CAS No. ：896705-16-1
| 产品名称: | BMH-21 |
| CAS No.: | 896705-16-1 |
| Chemical Name: | N-[2-(dimethylamino)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide |
| Synonyms: | BMH21 |
| 分子量: | 360.41 |
| 分子式: | C₂₁H₂₀N₄O₂ |
| SMILES: | O=C(C1=CC=CN2C1=NC3=C(C=C4C(C=CC=C4)=C3)C2=O)NCCN(C)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BMH-21是一种DNA嵌入剂 (DNA intercalator)，可抑制 RNA 聚合酶 I (Pol I) 转录。BMH-21 具有抗癌活性。 |
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Peltonen, K., Colis, L., Liu, H., et al.A targeting modality for destruction of RNA polymerase I that possesses anticancer activityCancer Cell25(1),77-90(2014)
Peltonen, K., Colis, L., Liu, H., et al.Identification of novel p53 pathway activating small-molecule compounds reveals unexpected similarities with known therapeutic agentsPLoS One5(9),e12996(2010)
