TH588
Cat. No.：YN290217
CAS No. ：1609960-31-7
| 产品名称: | TH588 |
| CAS No.: | 1609960-31-7 |
| Chemical Name: | N4-cyclopropyl-6-(2,3-dichlorophenyl)-2,4-pyrimidinediamine |
| Synonyms: | TH 588,TH-588,TH588 |
| 分子量: | 295.17 |
| 分子式: | C₁₃H₁₂Cl₂N₄ |
| SMILES: | NC1=NC(C2=CC=CC(Cl)=C2Cl)=CC(NC3CC3)=N1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TH588 是MTH1 (NUDT1)高效选择性抑制剂，IC50值 5 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Gad, H., Koolmeister, T., Jemth, A.S., et al.MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP poolNature508,215-242(2014)
