Nedaplatin
Cat. No.：YN290286
| 产品名称: | Nedaplatin |
| CAS No.: | 95734-82-0 |
| Chemical Name: | (SP-4-3)-diammine[2-(hydroxy-κO)acetato(2-)-κO]-platinum |
| Synonyms: | NSC 375101D |
| 分子量: | 303.18 |
| 分子式: | C₂H₈N₂O₃Pt |
| SMILES: | O=C1C[O-][Pt+2](N)(N)[O-]1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Nedaplatin (NSC 375101D) 是顺铂衍生物和DNA损伤剂。 |
| IC50和靶点: | |
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Uchida, N., Takeda, Y., Hojo, K., et al.Sequence-dependent antitumour efficacy of combination chemotherapy of nedaplatin, a novel platinum complex, with 5-fluorouracil in an in vivo murine tumour modelEur. J. Cancer34(11),1796-1801(1998)
Alberto, M.E., Lucas, M.F.A., Pavelka, M., et al.The second-generation anticancer drug Nedaplatin: A theoretical investigation on the hydrolysis mechanismJ. Phys. Chem. B113(43),14473-14479(2009)
Hanada, K., Suda, M., Kanai, N., et al.Pharmacokinetics and toxicodynamics of oxaliplatin in rats: Application of a toxicity factor to explain differences in the nephrotoxicity and myelosuppression induced by oxaliplatin and the other platinum antitumor derivativesPharm. Res.27(9),1893-1899(2010)
Tanaka, R., Takii, Y., Shibata, Y., et al.In vitro sequence-dependent interaction between nedaplatin and paclitaxel in human cancer cell linesCancer Chemother. Pharmacol.56(3),279-285(2005)
Yamada, H., Maki, H., Takeda, Y., et al.Evaluation of combined nedaplatin and docetaxel therapy for human head and neck cancer in vivoAnticancer Res.26(2A),989-994(2006)
