L189
Cat. No.:YN290355
产品名称: | L189 |
CAS No.: | 64232-83-3 |
Chemical Name: | 6-amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-thioxo-4(1H)-pyrimidinone |
Synonyms: | 4(1H)-Pyrimidinone,6-amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-thioxo-;L189;L-189;6-Amino-2,3-dihydro-5-[(phenylmethylene)amino]-2-4(1H)-pyrimidineone;6-amino-5-(benzylideneamino)-2-sulfanyl-4-pyrimidinol;6-amino-5-(benzylideneamino)-2-sulfanylidene- |
分子量: | 246.29 |
分子式: | C₁₁H₁₀N₄OS |
SMILES: | OC1=NC(S)=NC(N)=C1/N=C/C2=CC=CC=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | L189是一种新型人类DNA连接酶抑制剂, 抑制hLigI/ III/IV, IC50值分别为5/9/5 μM。 |
IC50和靶点: | |
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Chen, X., Zhong, S., Zhu, X., et al.Rational design of human DNA ligase inhibitors that target cellular DNA replication and repairCancer Res.68(9),3169-3177(2008)