6-Thio-2'-Deoxyguanosine
Cat. No.：YN290441
CAS No. ：789-61-7
| 产品名称: | 6-Thio-2'-Deoxyguanosine |
| CAS No.: | 789-61-7 |
| Chemical Name: | 2'-deoxy-6-thio-guanosine |
| Synonyms: | 6-thio-dG; β-TGdR |
| 分子量: | 283.31 |
| 分子式: | C₁₀H₁₃N₅O₃S |
| SMILES: | OC[C@@H]1[C@H](C[C@H](N2C=NC3=C2NC(N)=NC3=S)O1)O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 6-Thio-2'-Deoxyguanosine是一种核苷类似物，可以通过端粒酶掺入重新合成的端粒中。 |
| IC50和靶点: | |
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Schultz, D.C., Johnson, R.M., Ayyanathan, K., et al.Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2Nature604(7904),134-140(2022)
Mender, I., Gryaznov, S., Dikmen, Z.G., et al.Induction of telomere dysfunction mediated by the telomerase substrate precursor 6-thio-2'-deoxyguanosineCancer Discov.5(1),82-95(2015)
Mender, I., Zhang, A., Ren, Z., et al.Telomere stress potentiates STING-dependent anti-tumor immunityCancer Cell38(3),400-411(2020)
