LDC1267
Cat. No.：YN440214
CAS No. ：1361030-48-9
规格
价格(RMB)
库存
| 产品名称: | LDC1267 |
| CAS No.: | 1361030-48-9 |
| Chemical Name: | N-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-3-fluorophenyl]-4-ethoxy-1-(4-fluoro-2-methylphenyl)-1H-pyrazole-3-carboxamide |
| Synonyms: | LDC 1267,LDC-1267 |
| 分子量: | 560.55 |
| 分子式: | C₃₀H₂₆F₂N₄O₅ |
| SMILES: | FC1=CC(NC(C2=NN(C3=CC=C(F)C=C3C)C=C2OCC)=O)=CC=C1OC4=CC=NC5=CC(OC)=C(OC)C=C54 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | LDC1267 是TAM (Tyro3,Axl 和 Mer)激酶高效选择性抑制剂，对 Tyro3/Axl/MerIC50值分别为<5 nM/8 nM/29 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Paolino, M., Choidas, A., Wallner, S., et al.The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cellsNature507(7493),508-512(2014)
