UNC2881
Cat. No.:YN440347
产品名称: | UNC2881 |
CAS No.: | 1493764-08-1 |
Chemical Name: | 2-(butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-N-[[4-(1H-imidazol-1-yl)phenyl]methyl]-5-pyrimidinecarboxamide |
Synonyms: | UNC 2881; UNC-2881 |
分子量: | 463.58 |
分子式: | C₂₅H₃₃N₇O₂ |
SMILES: | CCCCNC1=NC(N[C@H]2CC[C@@H](O)CC2)=C(C(NCC3=CC=C(N4C=NC=C4)C=C3)=O)C=N1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | UNC2881是特异的Mer激酶抑制剂,能抑制稳态的Mer激酶磷酸化,IC50为22 nM。 |
IC50和靶点: | |
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Clinical Trial: | |
Solvent & Solubility: |
Zhang, W., McIver, A.L., Stashko, M.A., et al.Discovery of Mer specific tyrosine kinase inhibitors for the treatment and prevention of thrombosisJ. Med. Chem.56(23),9693-9700(2013)