SB-431542
Cat. No.：YN460003
CAS No. ：301836-41-9
| 产品名称: | SB-431542 |
| CAS No.: | 301836-41-9 |
| Chemical Name: | 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]-benzamide |
| Synonyms: | SB 431542,4-[4-(1,3-苯并二唑-5-基)-5-(2-吡啶基)-1H-咪唑-2-基]-苯酰胺水合物 |
| 分子量: | 384.39 |
| 分子式: | C₂₂H₁₆N₄O₃ |
| SMILES: | O=C(C1=CC=C(C=C1)C2=NC(C3=CC=C4OCOC4=C3)=C(N2)C5=NC=CC=C5)N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SB-431542 是一种有效，选择性的ALK5/TGF-β type I Receptor抑制剂，IC50值为 94 nM。 |
| IC50和靶点: | [{name:"ALK4:1 μM (IC50)"},{name: "ALK5:0.75 μM (IC50)"},{name: "ALK7:2 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Tobias, B., et al.: Cancer. Chemother. Pharmacol., 70, 221 (2012)
James, J., et al.: Molec. Cancer. Therap., 11, 930 (2012)
