ALK2-IN-1
Cat. No.:YN460007
CAS No. :2141955-96-4
产品名称: | ALK2-IN-1 |
CAS No.: | 2141955-96-4 |
Chemical Name: | 4-[6-[5-[4-ethoxy-1-(1-methylethyl)-4-piperidinyl]-2-pyridinyl]pyrrolo[1,2-b]pyridazin-4-yl]-1-piperazinecarboxylic acid, (3R)-tetrahydro-3-furanyl ester |
Synonyms: | ALK2-IN-1 |
分子量: | 562.70 |
分子式: | C₃₁H₄₂N₆O₄ |
SMILES: | O=C(N1CCN(C2=CC=NN3C2=CC(C4=NC=C(C5(OCC)CCN(C(C)C)CC5)C=C4)=C3)CC1)O[C@H]6COCC6 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | ALK2-IN-1 是一种活化素受体样激酶 2 (ALK2) 抑制剂,IC50<10 nM。详细信息请参考专利文献 WO2017181117A1 中的化合物 876。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Fleming, P.E., Hodous, B.L., Kim, J.L., et al.Inhibitors of activin receptor-like kinase,(2017)