LDN193189
Cat. No.：YN460009
| 产品名称: | LDN193189 |
| CAS No.: | 1062368-24-4 |
| Chemical Name: | 4-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline |
| Synonyms: | DM-3189 |
| 分子量: | 406.48 |
| 分子式: | C₂₅H₂₂N₆ |
| SMILES: | C1(C2=C3N=CC(C4=CC=C(N5CCNCC5)C=C4)=CN3N=C2)=CC=NC6=CC=CC=C16 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | LDN193189 是一种选择性的BMPI 型受体抑制剂，抑制ALK2和ALK3的IC50分别为 5 nM 和 30 nM。对 ALK4，ALK5 和 ALK7 的作用效果弱 (IC50≥500 nM)。 |
| IC50和靶点: | [{name:"ACVR1:5 nM (IC50)"},{name: "BMPR1A:30 nM (IC50)"}] |
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| Clinical Trial: | |
| Solvent & Solubility: |
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