LDN193189 Tetrahydrochloride
Cat. No.:YN460010
产品名称: | LDN193189 Tetrahydrochloride |
CAS No.: | 2310134-98-4 |
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Synonyms: | |
分子量: | 552.33 |
分子式: | C₂₅H₂₆Cl₄N₆ |
SMILES: | C1(C2=C3N=CC(C4=CC=C(N5CCNCC5)C=C4)=CN3N=C2)=CC=NC6=CC=CC=C16.Cl.Cl.Cl.Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | LDN193189 Tetrahydrochloride 是一种选择性的BMPI 型受体抑制剂,抑制ALK2和ALK3的IC50分别为 5 nM 和 30 nM。对 ALK4,ALK5 和 ALK7 的作用效果弱 (IC50≥500 nM)。 |
IC50和靶点: | [{name:"ACVR1:5 nM (IC50)"},{name: "BMPR1A:30 nM (IC50)"}] |
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