ITD-1
Cat. No.：YN460016
CAS No. ：1099644-42-4
| 产品名称: | ITD-1 |
| CAS No.: | 1099644-42-4 |
| Chemical Name: | 4-[1,1'-biphenyl]-4-yl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxo-3-quinolinecarboxylic acid, ethyl ester |
| Synonyms: | 4-[1,1'-联苯]-4-基-1,4,5,6,7,8-六氢-2,7,7-三甲基-5-氧代-3-喹啉羧酸乙酯 |
| 分子量: | 415.52 |
| 分子式: | C₂₇H₂₉NO₃ |
| SMILES: | O=C(C1=C(C)NC2=C(C(CC(C)(C)C2)=O)C1C3=CC=C(C4=CC=CC=C4)C=C3)OCC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ITD-1 是第一个选择性的TGFβ受体抑制剂，IC50为 460 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Schade, D., Lanier, M., Willems, E., et al.Synthesis and SAR of b-annulated 1,4-dihydropyridines define cardiomyogenic compounds as novel inhibitors of TGFβ signalingJ. Med. Chem.55(22),9946-9957(2012)
