PF-06952229
Cat. No.:YN460023
产品名称: | PF-06952229 |
CAS No.: | 1801333-55-0 |
Chemical Name: | |
Synonyms: | PF06952229 |
分子量: | 458.91 |
分子式: | C₂₃H₂₄ClFN₄O₃ |
SMILES: | O=C(NC(CO)CO)C1=CN=CC=C1NC2=CC(C3=CC(Cl)=CC=C3F)=NC=C2C(C)C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | PF-06952229 是一种强效、选择性和口服的TGFbR1抑制剂。PF-06952229 与 TGFbR1 特异性结合,阻止 TGFbR1 介导的信号转导。PF-06952229 是一种很有前途的抗肿瘤试剂 (antineoplastic agent),主要用于研究实体瘤,尤其是转移性乳腺癌。 |
IC50和靶点: | |
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