Vactosertib Hydrochloride
Cat. No.：YN460030
CAS No. ：1352610-25-3
| 产品名称: | Vactosertib Hydrochloride |
| CAS No.: | 1352610-25-3 |
| Chemical Name: | |
| Synonyms: | EW-7197 Hydrochloride; TEW-7197 Hydrochloride |
| 分子量: | 435.88 |
| 分子式: | C₂₂H₁₉ClFN₇ |
| SMILES: | CC1=CC=CC(C2=C(C3=CN4C(C=C3)=NC=N4)NC(CNC5=CC=CC=C5F)=N2)=N1.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Vactosertib Hydrochloride (EW-7197 Hydrochloride) 是一种有效的，具有口服活性且具有 ATP 竞争性激活素受体样激酶 5 (ALK5) 抑制剂，IC50为 12.9 nM。Vactosertib Hydrochloride 还以纳摩尔浓度抑制 ALK2 和 ALK4 (IC50为17.3 nM)。Vactosertib Hydrochloride 具有强大的抗转移活性和抗癌作用。 |
| IC50和靶点: | [{name:"ALK5:12.9 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
