A 77-01
Cat. No.:YN460031
产品名称: | A 77-01 |
CAS No.: | 607737-87-1 |
Chemical Name: | 4-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]-quinoline |
Synonyms: | A77-01 |
分子量: | 286.33 |
分子式: | C₁₈H₁₄N₄ |
SMILES: | CC1=CC=CC(C2=NNC=C2C3=CC=NC4=CC=CC=C34)=N1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | A 77-01 是一种有效的TGF-βI 型受体家族ALK5抑制剂,IC50值为 25 nM。 |
IC50和靶点: | |
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Tojo, M., Hamashima, Y., Hanyu, A., et al.The ALK-5 inhibitor A-83-01 inhibits Smad signaling and epithelial-to-mesenchymal transition by transforming growth factor-βCancer Sci.96(11),791-800(2005)