Hispidol
Cat. No.：YN270042
| 产品名称: | Hispidol |
| CAS No.: | 5786-54-9 |
| Chemical Name: | 6-hydroxy-2Z-[(4-hydroxyphenyl)methylene]-3(2H)-benzofuranone |
| Synonyms: | (Z) |
| 分子量: | 254.24 |
| 分子式: | C₁₅H₁₀O₄ |
| SMILES: | O=C1C2=CC=C(O)C=C2O/C1=C\C3=CC=C(O)C=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Hispidol ((Z)-Hispidol) 具有研究炎症性肠病的潜力，能够抑制TNF-α诱导的单核细胞对结肠上皮细胞的粘附，IC50值为 0.50 µM。 |
| IC50和靶点: | |
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Okombi, S., Rival, D., Bonnet, S., et al.Discovery of benzylidenebenzofuran-3(2H)-one (aurones) as inhibitors of tyrosinase derived from human melanocytesJ. Med. Chem.49(1),329-333(2006)
Wong, E.Occurrence and biosynthesis of 4′,6-dihydroxyaurone in soybeanPhytochem.5(3),463-467(1966)
Oh, J.M., Lee, H.-S., Baek, S.C., et al.Antidepressant-like activities of hispidol and decursin in mice and analysis of neurotransmitter monoaminesNeurochem. Res.45(8),1930-1940(2020)
Lim, H.J., Han, Y.T., Ahn, J.-H., et al.Longevity effects of hispidol in Caenorhabditis elegansBiofactors46(6),1041-1048(2020)
