DRI-C21045
Cat. No.:YN270140
CAS No. :2101765-81-3
产品名称: | DRI-C21045 |
CAS No.: | 2101765-81-3 |
Chemical Name: | |
Synonyms: | DRI C21045 |
分子量: | 580.61 |
分子式: | C₃₂H₂₄N₂O₇S |
SMILES: | O=S(C1=CC=CC2=CC=CC(NC(C3=CC=C(C4=CC=C(NC(C5=CC=C(C(OC)=O)C=C5)=O)C=C4)C=C3)=O)=C21)(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | DRI-C21045 (compound 10) 是一种有效和选择性的CD40-CD40L共刺激蛋白-蛋白质相互作用 (PPI) 抑制剂,IC50为 0.17 μM。DRI-C21045 显示对 CD40L 诱导的 NF-κB 活化和 B 细胞增殖的浓度依赖性抑制,IC50分别为 17.1 μM 和 4.5 μM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |