Hypaconitine
Cat. No.:YN270454
产品名称: | Hypaconitine |
CAS No.: | 6900-87-4 |
Chemical Name: | (1α,6α,14α,15α,16β)-1,6,16-trimethoxy-4-(methoxymethyl)-20-methyl-aconitane-8,13,14,15-tetrol, 8-acetate 14-benzoate |
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分子量: | 615.71 |
分子式: | C₃₃H₄₅NO₁₀ |
SMILES: | CO[C@@H](CC1)C23[C@@](C[C@@]4(O)[C@@H]5OC(C6=CC=CC=C6)=O)([H])[C@@]5([H])[C@](OC(C)=O)([C@@H](O)[C@@H]4OC)C7C2N(C)C[C@@]1(COC)[C@@]3([H])[C@H]7OC |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Hypaconitine 是从乌头属种分离到的高毒性的天然活性成分,广泛用于研究风湿病。 |
IC50和靶点: | |
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Muroi, M., Kimura, I., and Kimura, M.Blocking effects of hypaconitine and aconitine on nerve action potentials in phrenic nerve-diaphragm muscles of miceNeuropharmacology29(6),567-572(1990)
Nesterova, Y.V., Povetieva, T.N., Suslov, N.I., et al.Anti-inflammatory activity of diterpene alkaloids from Aconitum baikalenseBull. Exp. Biol. Med.156(5),665-668(2014)
Murayama, M., Mori, T., Bando, H., et al.Studies on the constituents of Aconitum species. IX. The pharmacological properties of pyro-type aconitine alkaloids, components of processed aconite powder 'kako-bushi-matsu': Analgesic, antiinflammatory and acute toxic activitiesJ. Ethnopharmacol.35(2),159-164(1991)