Geraniin
Cat. No.：YN270465
| 产品名称: | Geraniin |
| CAS No.: | 60976-49-0 |
| Chemical Name: | cyclic 2→7:4→5-(3,6-dihydro-2,9,10,11,11-pentahydroxy-3-oxo-2,6-methano-2H-1-benzoxocin-5,7-dicarboxylate) cyclic 3,6-(4,4′,5,5′,6,6′-hexahydroxy[1,1′-biphenyl]-2,2′-dicarboxylate) 1-(3,4,5-trihydroxybenzoate), β-D-glucopyranose, stereoisomer |
| Synonyms: | |
| 分子量: | 952.64 |
| 分子式: | C₄₁H₂₈O₂₇ |
| SMILES: | O=C(OC[C@H](O[C@@H](OC(C1=CC(O)=C(O)C(O)=C1)=O)[C@H]2OC3=O)[C@H](OC(C(C4C5=C3C=C(O)C(O)=C5OC6(O)C4(O)O)=CC6=O)=O)[C@H]2O7)C8=CC(O)=C(O)C(O)=C8C9=C(O)C(O)=C(O)C=C9C7=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Geraniin 是具有抗肿瘤、抗炎、抗高血糖活性的、肿瘤坏死因子α(TNF-α)的释放抑制剂，其IC50值为 43 μM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Lin, S.-Y., Wang, C.-C., Lu, Y.-L., et al.Antioxidant, anti-semicarbazide-sensitive amine oxidase, and anti-hypertensive activities of geraniin isolated from Phyllanthus urinariaFood Chem. Toxicol.46,2485-2492(2008)
Yang, C.-M., Cheng, H.-Y., Lin, T.-C., et al.The in vitro activity of geraniin and 1,3,4,6-tetra-O-galloyl-β-D-glucose isolated from Phyllanthus urinaria against herpes simplex virus type 1 and type 2 infectionJ. Ethnopharmacol.110(3),555-558(2007)
Li, J., Wang, S., Yin, J., et al.Geraniin induces apoptotic cell death in human lung adenocarcinoma A549 cells in vitro and in vivoCan. J. Physiol. Pharmacol.91(12),1016-1024(2013)
