N-Formyl-Met-Leu-Phe
Cat. No.:YN270599
产品名称: | N-Formyl-Met-Leu-Phe |
CAS No.: | 59880-97-6 |
Chemical Name: | N-formyl-L-methionyl-L-leucyl-L-phenylalanine |
Synonyms: | fMLP; N-Formyl-MLF |
分子量: | 437.55 |
分子式: | C₂₁H₃₁N₃O₅S |
SMILES: | O=C(O)[C@H](CC1=CC=CC=C1)NC([C@H](CC(C)C)NC([C@H](CCSC)NC=O)=O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | N-Formyl-Met-Leu-Phe (fMLP; N-Formyl-MLF) 是一种趋化肽和N-甲酰基肽受体 (FPR) 的特异性配体。报道显示N-Formyl-Met-Leu-Ph 可抑制TNF-alpha的分泌。 |
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Panaro, M.A., Acquafreddo, A., Sisto, M., et al.Biological role of the N-formyl peptide receptorsImmunopharmacol. Immunotoxicol.28(1),103-127(2006)
Wang, W., Li, T., Wang, X., et al.FAM19A4 is a novel cytokine ligand of formyl peptide receptor 1 (FPR1) and is able to promote the migration and phagocytosis of macrophagesCell. Mol. Immunol.12(5),615-624(2015)
Colucci, M., Mastriota, M., Maione, F., et al.Guinea pig ileum motility stimulation elicited by N-formyl-Met-Leu-Phe (fMLF) involves neurotransmitters and prostanoidsPeptides32(2),266-271(2011)