Desmorpholinyl Quizartinib-PEG2-COOH
Cat. No.:YN430199
产品名称: | Desmorpholinyl Quizartinib-PEG2-COOH |
CAS No.: | 2292116-14-2 |
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分子量: | 607.68 |
分子式: | C₃₀H₃₃N₅O₇S |
SMILES: | O=C(O)CCOCCOCCOC1=CC=C2N3C(SC2=C1)=NC(C4=CC=C(NC(NC5=NOC(C(C)(C)C)=C5)=O)C=C4)=C3 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Desmorpholinyl Quizartinib-PEG2-COOH 包含靶蛋白 FLT-3 配体和一种基于 PEG 的 PROTAC Linker。Desmorpholinyl Quizartinib-PEG2-COOH 可用于合成 PROTAC FLT-3 degrader 1 (HY-114323)。PROTAC FLT-3 degrader 1 是 PROTACFLT-3 ITD降解剂,IC50为 0.6 nM。 |
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