ONX 0801 trisodium
Cat. No.：YN270077
| 产品名称: | ONX 0801 trisodium |
| CAS No.: | 1097638-00-0 |
| Chemical Name: | N-[4-[2-Propynyl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-1H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-L-γ-glutamyl-D-Glutamic Acid Trisodium Salt;N-[4-[2-Propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl |
| Synonyms: | BGC 945 trisodium; Idetrexed trisodium; CB 300945 trisodium |
| 分子量: | 713.58 |
| 分子式: | C₃₂H₃₀N₅Na₃O₁₀ |
| SMILES: | O=C(N[C@H](C(O[Na])=O)CCC(N[C@@H](C(O[Na])=O)CCC(O[Na])=O)=O)C1=CC=C(N([C@H]2CCC3=C2C=C4C(NC(CO)=NC4=O)=C3)CC#C)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ONX 0801 (BGC 945) trisodium 是胸腺激酶合成酶(TS)的抑制剂，靶向α 叶酸受体过表达的肿瘤。 |
| IC50和靶点: | |
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| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Tochowicz, A. et al.: J. Med. Chem., 56, 5446 (2013)
