Tiratricol
Cat. No.：YN481996
| 产品名称: | Tiratricol |
| CAS No.: | 51-24-1 |
| Chemical Name: | 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-benzeneacetic acid |
| Synonyms: | 3,3',5-Triiodothyroacetic acid |
| 分子量: | 621.93 |
| 分子式: | C₁₄H₉I₃O₄ |
| SMILES: | O=C(O)CC1=CC(I)=C(OC2=CC=C(O)C(I)=C2)C(I)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tiratricol是甲状腺激素类似物, 已被用来抑制垂体促甲状腺激素分泌, 降低垂体外拟甲状腺素药效。 |
| IC50和靶点: | |
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Oka, T., Mitsui-Watanabe, N., Tatarazako, N., et al.Establishment of transactivation assay systems using fish, amphibian, reptilian and human thyroid hormone receptorsJ. Appl. Toxicol.33(9),991-1000(2013)
Kersseboom, S., Horn, S., Visser, W.E., et al.In vitro and mouse studies supporting therapeutic utility of triiodothyroacetic acid in MCT8 deficiencyMol. Endocrinol.28(12),1961-1970(2014)
Alvarez, L., Burgueño, A., Zeni, S., et al.Comparison of the effects of 3,5,3'-triiodothyroacetic acid and triiodothyronine on goiter prevention and involution and on hepatic and skeletal parameters in ratsHorm. Metab. Res.36(5),291-297(2004)
Ha, H.C., Jang, J.M., Zhou, D., et al.3, 5, 3'-Triiodothyroacetic acid (TRIAC) is an anti-inflammatory drug that targets toll-like receptor 2Arch. Pharm. Res.41(10),996-1008(2018)
