Eprotirome
Cat. No.：YN480268
CAS No. ：355129-15-6
规格
价格(RMB)
库存
| 产品名称: | Eprotirome |
| CAS No.: | 355129-15-6 |
| Chemical Name: | 3-[[3,5-dibromo-4-[4-hydroxy-3-(1-methylethyl)phenoxy]phenyl]amino-3-oxo-propanoic acid |
| Synonyms: | KB2115 |
| 分子量: | 487.14 |
| 分子式: | C₁₈H₁₇Br₂NO₅ |
| SMILES: | O=C(O)CC(NC1=CC(Br)=C(OC2=CC=C(O)C(C(C)C)=C2)C(Br)=C1)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Eprotirome (KB2115) 是肝脏选择性甲状腺激素受体 (thyroid hormone receptor, TR) 激动剂。KB2115 对TRβ的亲和力略高于TRα。Eprotirome 降低了低密度脂蛋白 (LDL) 胆固醇的浓度，可用于血脂异常和肥胖症的研究。 |
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Berkenstam, A., Kristensen, J., Mellström, K., et al.The thyroid hormone mimetic compound KB2115 lowers plasma LDL cholesterol and stimulates bile acid synthesis without cardiac effects in humansProc. Natl. Acad. Sci. USA105(2),663-667(2008)
