9-amino-CPT
Cat. No.：YN290006
| 产品名称: | 9-amino-CPT |
| CAS No.: | 91421-43-1 |
| Chemical Name: | (4S)-10-amino-4-ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione |
| Synonyms: | 9-氨基喜树碱; 9-amino-20(S)-camptothecin |
| 分子量: | 363.37 |
| 分子式: | C₂₀H₁₇N₃O₄ |
| SMILES: | O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=CC5=C(N)C=CC=C5N=C4C3=C2)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 9-amino-CPT (9-amino-20(S)-camptothecin) 是拓扑异构酶I的抑制剂，具有有效地抗肿瘤活性。 |
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Drwal, M.N., Agama, K., Wakelin, L.P.G., et al.Exploring DNA topoisomerase I ligand space in search of novel anticancer agentsPLoS One6(9),1-12(2011)
Rothenberg, M.L.Topoisomerase I inhibitors: Review and updateAnn. Oncol.8(9),837-855(1997)
Dancey, J., and Eisenhauer, E.A.Current perspectives on camptothecins in cancer treatmentBr. J. Cancer74(3),327-338(1996)
