CH-0793076
Cat. No.：YN290072
| 产品名称: | CH-0793076 |
| CAS No.: | 534605-78-2 |
| Chemical Name: | |
| Synonyms: | TP3076 |
| 分子量: | 458.51 |
| 分子式: | C₂₆H₂₆N₄O₄ |
| SMILES: | O=C1[C@](O)(CC)C(C=C23)=C(CO1)C(N2CC(C3=N4)=C5N(CCCCC)C=NC6=C5C4=CC=C6)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CH-0793076 (TP3076)，喜树碱的六环类似物，是TP300 的活性药物和主要代谢物。CH-0793076 抑制 DNA 拓扑异构酶I (DNA topoisomerase I)，IC50为 2.3 μM。CH-0793076 对表达 BCRP (乳腺癌耐药蛋白) 的细胞也有活性。 |
| IC50和靶点: | [{name:"Topoisomerase I:2.3 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
