Ellipticine hydrochloride
Cat. No.：YN290367
CAS No. ：5081-48-1
| 产品名称: | Ellipticine hydrochloride |
| CAS No.: | 5081-48-1 |
| Chemical Name: | 5,11-dimethyl-6H-pyrido[4,3-b]carbazole, monohydrochloride |
| Synonyms: | 玫瑰树碱盐酸盐; NSC 71795 hydrochloride |
| 分子量: | 282.77 |
| 分子式: | C₁₇H₁₅ClN₂ |
| SMILES: | CC1=C(C=NC=C2)C2=C(C)C(N3)=C1C4=C3C=CC=C4.Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Ellipticine (NSC 71795) hydrochloride是一种有效的抗肿瘤剂; 抑制DNA拓扑异构酶II活性。 |
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Kohn, K.W., Waring, M.J., Glaubiger, D., et al.Intercalative binding of ellipticine to DNACancer Res.35(1),71-76(1975)
Stiborová, M., Poljakova, J., Martinkova, E., et al.Ellipticine cytotoxicity to cancer cell lines - a comparative studyInterdiscip. Toxicol.4(2),98-105(2011)
Aimová, D., Svobodová, L., Kotrbová, V., et al.The anticancer drug ellipticine is a potent inducer of rat cytochromes P450 1A1 and 1A2, thereby modulating its own metabolismDrug Metab. Dispos.35(10),1926-1934(2007)
