SW044248
Cat. No.：YN290460
CAS No. ：522650-83-5
| 产品名称: | SW044248 |
| CAS No.: | 522650-83-5 |
| Chemical Name: | 2-[(5-ethyl-5H-1,2,4-triazino[5,6-b]indol-3-yl)thio]-N-(2-methoxyphenyl)-butanamide |
| Synonyms: | SW 044248,SW044248 |
| 分子量: | 421.52 |
| 分子式: | C₂₂H₂₃N₅O₂S |
| SMILES: | CCC(SC1=NN=C2C(N(CC)C3=C2C=CC=C3)=N1)C(NC4=CC=CC=C4OC)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SW044248 是一种非典型的拓扑异构酶 I (topoisomerase I) 抑制剂，可以选择性地对某些非小细胞肺癌细胞产生毒性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Zubovych, I.O., Sethi, A., Kulkarni, A., et al.A novel inhibitor of topoisomerase I is selectively toxic for a subset of non-small cell lung cancer cell linesMol. Cancer Ther.15(1),23-36(2016)
