Proscillaridin A
Cat. No.:YN290519
产品名称: | Proscillaridin A |
CAS No.: | 466-06-8 |
Chemical Name: | A 32686; Caradrin; Cardion; Cardiovite; Carmazon; Coratol; Desglucotransvaaline; Desglucotrnasvaaline; Herzo Proscillan; NSC 7521; PSC-801; Procardin; Procilan; Proscillan; Proscillaridin; Proslladin; Prostosin; Proszine; Protasin; Purosin-TC; Sandoscill; |
Synonyms: | |
分子量: | 530.65 |
分子式: | C₃₀H₄₂O₈ |
SMILES: | O[C@@]([C@@]1(CC2)C)(CC[C@@H]1C(C=C3)=COC3=O)[C@@](CCC4=C[C@@H](O[C@@](O[C@@H](C)[C@H](O)[C@H]5O)([H])[C@@H]5O)CC6)([H])[C@@]2([H])[C@]46C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Proscillaridin A 是强力的拓扑异构酶 I 和 IItopoisomerase I/II抑制剂,抑制拓扑异构酶 I 和 II 的IC50值分别为 30 nM 和 100 nM。 |
IC50和靶点: | [{name:"Topoisomerase I:30 nM (IC50)"},{name: "Topoisomerase II:100 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Prassas, I. and Diamandis, E. P.:В Nat. Rev. Drug Discov.В 7, 926 (2008)
Milutinovic, S., et al.: PloS One 11,В e0152692/1 (2016)
Bielawski, K., et al.: ‎Biol. Pharm. Bull 29, 1493 (2006)