Trk-IN-4
Cat. No.：YN380050
CAS No. ：1799788-94-5
| 产品名称: | Trk-IN-4 |
| CAS No.: | 1799788-94-5 |
| Chemical Name: | |
| Synonyms: | PF-6683324 isomer |
| 分子量: | 521.46 |
| 分子式: | C₂₄H₂₃F₄N₅O₄ |
| SMILES: | O=C(N)C1=C(O[C@H]2CCN(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)C[C@H]2F)N=CC(C4=CN(C)C=N4)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Trk-IN-4 (PF-6683324 isomer) 是一种有效的pan-Trk抑制剂，抑制TrkA，TrkB和TrkC细胞，IC50分别为 1.9 nM，2.6 nM 和 1.1 nM。具有抗痛觉过敏作用。 |
| IC50和靶点: | [{name:"TrkA:1.9 nM (IC50, in cell-based assays)"},{name: "TrkB:2.6 nM (IC50, in cell-based assays)"},{name: "TrkC:1.1 nM (IC50, in cell-based assays)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
