ANA-12
Cat. No.：YN380064
| 产品名称: | ANA-12 |
| CAS No.: | 219766-25-3 |
| Chemical Name: | N-[2-[[(hexahydro-2-oxo-1H-azepin-3-yl)amino]carbonyl]phenyl]-benzo[b]thiophene-2-carboxamide |
| Synonyms: | ANA12,ANA 12 |
| 分子量: | 407.49 |
| 分子式: | C₂₂H₂₁N₃O₃S |
| SMILES: | O=C(C1=CC2=CC=CC=C2S1)NC3=CC=CC=C3C(NC4C(NCCCC4)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ANA-12是有效，选择性的TrkB拮抗剂，对高亲和力和低亲和力位点的IC50分别为45.6 nM和41.1 μM。 |
| IC50和靶点: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
Cazorla, M., Prémont, J., Mann, A., et al.Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in miceJ. Clin. Invest.121(5),1846-1857(2011)
