ZK168281
Cat. No.：YN470008
CAS No. ：186371-96-0
规格
价格(RMB)
库存
| 产品名称: | ZK168281 |
| CAS No.: | 186371-96-0 |
| Chemical Name: | (2E)-3-[1-[(1R,2E,4R)-4-[(1R,3aS,4E,7aR)-4-[(2Z)-2-[(3S,5R)-3,5-Dihydroxy-2-methylenecyclohexylidene]ethylidene]octahydro-7a-methyl-1H-inden-1-yl]-1-hydroxy-2-penten-1-yl]cyclopropyl]-2-propenoic Acid Ethyl Ester; (2E)-3-[1-[(1α,3β,5Z,7E,22E,24R)-1,3,24-T |
| Synonyms: | |
| 分子量: | 510.70 |
| 分子式: | C₃₂H₄₆O₅ |
| SMILES: | O=C(OCC)/C=C/C1([C@H](O)/C=C/[C@H]([C@H]2CC[C@@]3([H])/C(CCC[C@]23C)=C/C=C4C([C@@H](O)C[C@H](O)C\4)=C)C)CC1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | ZK168281 是一种 1α,25(OH)2D3类似物，也是一种纯VDR拮抗剂，Kd值为 0.1 nM。ZK168281 是其受体 CoA 相互作用的有效抑制剂。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Lempiainen, H., et al.: Mol. Endocrinol., 19, 2258 (2005)
Vaeisaenen, S., et al.: 315, 229 (2002)
