NVP-BAW2881
Cat. No.:YN440010
产品名称: | NVP-BAW2881 |
CAS No.: | 861875-60-7 |
Chemical Name: | 6-[(2-amino-4-pyrimidinyl)oxy]-N-[3-(trifluoromethyl)phenyl]-1-naphthalenecarboxamide |
Synonyms: | BAW2881 |
分子量: | 424.38 |
分子式: | C₂₂H₁₅F₃N₄O₂ |
SMILES: | O=C(C1=C2C=CC(OC3=NC(N)=NC=C3)=CC2=CC=C1)NC4=CC=CC(C(F)(F)F)=C4 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | NVP-BAW2881 (BAW2881) 是有效,选择性的VEGFR2抑制剂,IC50为值9 nM。 |
IC50和靶点: | [{name:"VEGFR1:820 nM (IC50)"},{name: "VEGFR2:9 nM (IC50)"},{name: "VEGFR3:420 nM (IC50)"},{name: "Tie2:650 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Halin, C., Fahrngruber, H., Meingassner, J.G., et al.Inhibition of chronic and acute skin inflammation by treatment with a vascular endothelial growth factor receptor tyrosine kinase inhibitorAm. J. Pathol.173(1),265-277(2008)