BFH772
Cat. No.:YN440011
产品名称: | BFH772 |
CAS No.: | 890128-81-1 |
Chemical Name: | 6-[[6-(hydroxymethyl)-4-pyrimidinyl]oxy]-N-[3-(trifluoromethyl)phenyl]-1-naphthalenecarboxamide |
Synonyms: | BFH 772, BFH-772 |
分子量: | 439.39 |
分子式: | C₂₃H₁₆F₃N₃O₃ |
SMILES: | O=C(NC1=CC(C(F)(F)F)=CC=C1)C2=CC=CC3=CC(OC4=NC=NC(CO)=C4)=CC=C32 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | BFH772 是一种有效的,具有口服活性的VEGFR2抑制剂,IC50为 3 nM。 |
IC50和靶点: | [{name:"VEGFR2:3 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Bold, G., Schnell, C., Furet, P., et al.A novel potent oral series of VEGFR2 inhibitors abrogate tumor growth by inhibiting angiogenesisJ. Med. Chem.59(1),132-146(2016)