Vatalanib dihydrochloride
Cat. No.：YN440182
CAS No. ：212141-51-0
规格
价格(RMB)
库存
| 产品名称: | Vatalanib dihydrochloride |
| CAS No.: | 212141-51-0 |
| Chemical Name: | N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine, dihydrochloride |
| Synonyms: | PTK787 dihydrochloride; CGP-797870 dihydrochloride; ZK-222584 dihydrochloride |
| 分子量: | 419.73 |
| 分子式: | C₂₀H₁₇Cl₃N₄ |
| SMILES: | ClC1=CC=C(C=C1)NC2=NN=C(C3=C2C=CC=C3)CC4=CC=NC=C4.[H]Cl.[H]Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Vatalanib dihydrochloride (PTK787 dihydrochloride) 是VEGFR2/KDR的抑制剂，其IC50值为37nM。 |
| IC50和靶点: | [{name:"VEGFR2:37 nM (IC50)"}] |
| In Vitro: | |
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| Clinical Trial: | |
| Solvent & Solubility: |
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Giatromanolaki, A., Koukourakis, M., Sivridis, E., et al.Vascular density analysis in colorectal cancer patients treated with vatalanib (PTK787/ZK222584) in the randomised CONFIRM trialsBr. J. Cancer107(7),1044-1050(2012)
