Cabozantinib S-malate
Cat. No.：YN440186
CAS No. ：1140909-48-3
规格
价格(RMB)
库存
| 产品名称: | Cabozantinib S-malate |
| CAS No.: | 1140909-48-3 |
| Chemical Name: | N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (2S)-2-Hydroxybutanedioic Acid; Cabozantinib S-Malate; XL 184; |
| Synonyms: | 卡博替尼苹果酸盐; XL184 S-malate; BMS-907351 S-malate |
| 分子量: | 635.59 |
| 分子式: | C₃₂H₃₀FN₃O₁₀ |
| SMILES: | O=C([C@H](CC(O)=O)O)O.O=C(NC1=CC=C(C=C1)OC2=CC=NC3=CC(OC)=C(C=C23)OC)C4(CC4)C(NC5=CC=C(C=C5)F)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cabozantinib S-malate (XL184 S-malate) 是一种有效的多受体酪氨酸激酶抑制剂， 抑制VEGFR2，c-Met，Kit，Axl和Flt3的IC50分别为0.035，1.3，4.6，7 和 11.3 nM。 |
| IC50和靶点: | [{name:"VEGFR2:0.035 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Camp, R., et al.: Cancer, 86, 2259
