SAR131675
Cat. No.：YN440320
CAS No. ：1433953-83-3
规格
价格(RMB)
库存
| 产品名称: | SAR131675 |
| CAS No.: | 1433953-83-3 |
| Chemical Name: | 2-amino-1-ethyl-1,4-dihydro-7-[(3R)-3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl]-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide |
| Synonyms: | SAR 131675 |
| 分子量: | 358.39 |
| 分子式: | C₁₈H₂₂N₄O₄ |
| SMILES: | O=C1C(C(NC)=O)=C(N)N(CC)C2=NC(C#C[C@@](COC)(C)O)=CC=C21 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SAR131675是有效，选择性的VEGFR3抑制剂，IC50值为23 nM。 |
| IC50和靶点: | [{name:"VEGFR3:23 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Alam, A., Blanc, I., Gueguen-Dorbes, G., et al.SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic activitiesMol. Cancer Ther.11(8),1637-1649(2012)
