Dynasore
Cat. No.：YN250630
| 产品名称: | Dynasore |
| CAS No.: | 304448-55-3 |
| Chemical Name: | 3-hydroxy-2-[(3,4-dihydroxyphenyl)methylene]hydrazide-2-naphthalenecarboxylic acid |
| Synonyms: | Dynamin Inhibitor I |
| 分子量: | 322.31 |
| 分子式: | C₁₈H₁₄N₂O₄ |
| SMILES: | O=C(C1=C(O)C=C2C=CC=CC2=C1)N/N=C/C3=CC=C(O)C(O)=C3 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dynasore是可渗透细胞的发动蛋白抑制剂，IC50为15 μM。 |
| IC50和靶点: | |
| In Vitro: | |
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| Solvent & Solubility: |
Macia, E., Ehrlich, M., Massol, R., et al.Dynasore, a cell-permeable inhibitor of dynaminDev. Cell10(6),839-850(2006)
Kirchhausen, T., Macia, E., and Pelish, H.E.Use of dynasore, the small molecule inhibitor of dynamin, in the regulation of endocytosisMethods Enzymol.438,77-93(2008)
Chen, C.L., Hou, W.H., Liu, I.H., et al.Inhibitors of clathrin-dependent endocytosis enhance TGFβ signaling and responsesJ. Cell Sci.122,1863-1871(2009)
Barrias, E.S., Reignault, L.C., de Souza, W., et al.Dynasore, a dynamin inhibitor, inhibits Trypanosoma cruzi entry into peritoneal macrophagesPLoS One5(1),(2010)
de la Vega, M., Marin, M., Kondo, N., et al.Inhibition of HIV-1 endocytosis allows lipid mixing at the plasma membrane, but not complete fusionRetrovirology8(99),(2011)
Douthitt, H.L., Luo, F., McCann, S.D., et al.Dynasore, an inhibitor of dynamin, increases the probability of transmitter releaseNeuroscience172,187-195(2011)
Seil, M., El Ouaaliti, M., and Dehaye, J.P.Secretion of IL-1β triggered by dynasore in murine peritoneal macrophagesInnate Immun.18(2),241-249(2012)
