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Probucol

Cat. No.:YN251026

  • CAS No. :23288-49-5

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    • 生物活性
    • 参考文献
    • 产品名称: Probucol
      CAS No.: 23288-49-5
      Chemical Name: 4,4'-[(1-methylethylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)-phenol
      Synonyms:普罗布考; DH-581
      分子量:516.84
      分子式:C₃₁H₄₈O₂S₂
      SMILES:CC(SC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)(SC2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2)C
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Probucol (DH-581) 能抗血脂过多,能通过增加LDL的代谢率降低血液中的胆固醇水平。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Yamamoto, A.A uniqe antilipidemic drug--ProbucolJ. Atheroscler. Thromb.15(6),304-305(2013)

      Favari, E., Zanotti, I., Zimetti, F., et al.Probucol inhibits ABCA1-mediated cellular lipid effluxArterioscler. Thromb. Vasc. Biol.24(12),2345-2350(2004)

      Colle, D., Santos, D.B., Moreira, E.L.G., et al.Probucol increases striatal glutathione peroxidase activity and protects against 3-nitropropionic acid-induced pro-oxidative damage in ratsPLoS One8(6),e67658(2013)

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