Probucol
Cat. No.:YN251026
产品名称: | Probucol |
CAS No.: | 23288-49-5 |
Chemical Name: | 4,4'-[(1-methylethylidene)bis(thio)]bis[2,6-bis(1,1-dimethylethyl)-phenol |
Synonyms: | 普罗布考; DH-581 |
分子量: | 516.84 |
分子式: | C₃₁H₄₈O₂S₂ |
SMILES: | CC(SC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)(SC2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2)C |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Probucol (DH-581) 能抗血脂过多,能通过增加LDL的代谢率降低血液中的胆固醇水平。 |
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Yamamoto, A.A uniqe antilipidemic drug--ProbucolJ. Atheroscler. Thromb.15(6),304-305(2013)
Favari, E., Zanotti, I., Zimetti, F., et al.Probucol inhibits ABCA1-mediated cellular lipid effluxArterioscler. Thromb. Vasc. Biol.24(12),2345-2350(2004)
Colle, D., Santos, D.B., Moreira, E.L.G., et al.Probucol increases striatal glutathione peroxidase activity and protects against 3-nitropropionic acid-induced pro-oxidative damage in ratsPLoS One8(6),e67658(2013)