Schisandrin C
Cat. No.:YN251522
CAS No. :61301-33-5
产品名称: | Schisandrin C |
CAS No.: | 61301-33-5 |
Chemical Name: | (6R,7S,13aS)-5,6,7,8-tetrahydro-13,14-dimethoxy-6,7-dimethyl-cycloocta[1,2-f:3,4-f']bis[1,3]benzodioxole |
Synonyms: | 五味子丙素; Schizandrin-C; Wuweizisu-C |
分子量: | 384.42 |
分子式: | C₂₂H₂₄O₆ |
SMILES: | C[C@H]([C@H](C)C1)CC2=C(C3=C1C=C4OCOC4=C3OC)C(OC)=C5OCOC5=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 五味子丙素(Schisandrin C)是从北五味子木脂素的分离出的天然化合物,在U937细胞中显示有抗癌活性。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Li, X.Y.Bioactivity of neolignans from fructus SchizandraeMem. Inst. Oswaldo Cruz86 Suppl 2,31-37(1991)
Park, C., Choi, Y.-W., Hyun, S.K., et al.Induction of G1 arrest and apoptosis by schisandrin C isolated from Schizandra chinensis Baill in human leukemia U937 cellsInt. J. Mol. Med.24(4),495-502(2009)
Kim, J.S., and Yi, H.K.Schisandrin C enhances mitochondrial biogenesis and autophagy in C2C12 skeletal muscle cells: Potential involvement of anti-oxidative mechanismsNaunyn Schmiedebergs Arch. Pharmacol.391(2),197-206(2018)
Park, S.Y., Park, S.J., Park, T.G., et al.Schizandrin C exerts anti-neuroinflammatory effects by upregulating phase II detoxifying/antioxidant enzymes in microgliaInt. Immunopharmacol.17(2),415-426(2013)
Jiang, Y., Fan, X., Wang, Y., et al.Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivationChem. Biol. Interact.231,83-89(2015)