MSAB
Cat. No.：YN450049
CAS No. ：173436-66-3
规格
价格(RMB)
库存
| 产品名称: | MSAB |
| CAS No.: | 173436-66-3 |
| Chemical Name: | 3-[[(4-methylphenyl)sulfonyl]amino]-benzoic acid, methyl ester |
| Synonyms: | |
| 分子量: | 305.35 |
| 分子式: | C₁₅H₁₅NO₄S |
| SMILES: | O=C(C1=CC=CC(NS(=O)(C2=CC=C(C=C2)C)=O)=C1)OC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | MSAB 是Wnt/β-catenin信号传导的有效和选择性抑制剂。MSAB 与 β-catenin 结合，促进其降解，并特别下调 Wnt/β-catenin 靶基因。MSAB 对 Wnt 依赖性癌细胞显示出有效的抗肿瘤作用。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Hwang, S.-Y., Deng, X., Byun, S., et al.Direct targeting of β-catenin by a small molecule stimulates proteasomal degradation and suppresses oncogenic Wnt/β-catenin signalingCell Rep.16(1),28-36(2016)
