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> 产品中心 > 抑制剂 & 激动剂 > Stem Cell/Wnt > Wnt

IWP-4

Cat. No.:YN450070

  • CAS No. :686772-17-8

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    • 产品名称: IWP-4
      CAS No.: 686772-17-8
      Chemical Name: N-(6-methyl-2-benzothiazolyl)-2-[[3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl]thio]-acetamide
      Synonyms:Inhibitor of Wnt Production-4
      分子量:496.62
      分子式:C₂₃H₂₀N₄O₃S₃
      SMILES:O=C(NC1=NC2=CC=C(C)C=C2S1)CSC3=NC(CCS4)=C4C(N3C5=CC=CC=C5OC)=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: IWP-4 是一种小分子Wnt抑制剂,其IC50值为 25 nM。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Chen, B., Dodge, M.E., Tang, W., et al.Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancerNat. Chem. Biol.5(2),100-107(2009)

      Lian, X., Hsiao, C., Wilson, G., et al.Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signalingProc. Natl. Acad. Sci. USA,E1848-E1857(2012)

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