Pyrvinium pamoate
Cat. No.：YN450134
CAS No. ：3546-41-6
规格
价格(RMB)
库存
| 产品名称: | Pyrvinium pamoate |
| CAS No.: | 3546-41-6 |
| Chemical Name: | 4,4′-methylenebis[3-hydroxy-2-naphthalenecarboxylate] 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-quinolinium |
| Synonyms: | Pyrvinium embonate |
| 分子量: | 575.70 |
| 分子式: | C₂₆H₂₈N₃ . ₁/₂ C₂₃H₁₄O₆ |
| SMILES: | C[N+]1=C2C=CC(N(C)C)=CC2=CC=C1/C=C/C3=C(C)N(C4=CC=CC=C4)C(C)=C3.C[N+]5=C6C=CC(N(C)C)=CC6=CC=C5/C=C/C7=C(C)N(C8=CC=CC=C8)C(C)=C7.O=C(C9=C(O)C(CC%10=C%11C=CC=CC%11=CC(C([O-])=O)=C%10O)=C%12C=CC=CC%12=C9)[O-] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Pyrvinium pamoate是FDA批准的抗蠕虫药物，抑制WNT通路信号传导。 |
| IC50和靶点: | |
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Brody, G.L., and Elward, T.E.Comparative activity of 29 known anthelmintics under standardized drug-diet and gavage medication regimens against four helminth species in miceJ. Parasitol.57(5),1068-1077(1971)
Esumi, H., Lu, J., Kurashima, Y., et al.Antitumor activity of pyrvinium pamoate, 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-quinolinium pamoate salt, showing preferential cytotoxicity during glucose starvationCancer Sci.95(8),685-690(2004)
Van Acker, H.H., Capsomidis, A., Smits, E.L., et al.CD56 in the immune system: More than a marker for cytotoxicity?Front. Immunol.8,892(2017)
