ML-7 hydrochloride
Cat. No.:YN450098
产品名称: | ML-7 hydrochloride |
CAS No.: | 110448-33-4 |
Chemical Name: | hexahydro-1-[(5-iodo-1-naphthalenyl)sulfonyl]-1H-1,4-diazepine, monohydrochloride |
Synonyms: | ML-7盐酸盐,ML-7 HCl |
分子量: | 452.74 |
分子式: | C₁₅H₁₈ClIN₂O₂S |
SMILES: | O=S(N1CCNCCC1)(C2=C3C=CC=C(I)C3=CC=C2)=O.[H]Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | ML-7 hydrochloride 是一种萘磺酰胺衍生物,有效抑制MLCK(IC50=300 nM)。ML-7 hydrochloride 也是一种YAP/TAZ抑制剂。 |
IC50和靶点: | |
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Saitoh, M., Ishikawa, T., Matsushima, S., et al.Selective inhibition of catalytic activity of smooth muscle myosin light chain kinaseJ. Biol. Chem.262(16),7796-7801(1987)
Bain, J., McLauchlan, H., Elliot, M., et al.The specificities of protein kinase inhibitors: An updateBiochem. J.371(Pt. 1),199-204(2003)