RG14620
Cat. No.:YN340024
CAS No. :136831-49-7
产品名称: | RG14620 |
CAS No.: | 136831-49-7 |
Chemical Name: | α-[(3,5-dichlorophenyl)methylene]-3-pyridineacetonitrile |
Synonyms: | Tyrphostin RG14620 |
分子量: | 275.13 |
分子式: | C₁₄H₈Cl₂N₂ |
SMILES: | N#C/C(C1=CC=CN=C1)=C/C2=CC(Cl)=CC(Cl)=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | RG14620是EGFR抑制剂;IC50值为3 μM。 |
IC50和靶点: | [{name:"EGFR:3 μM (IC50, Cell Assay)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Gazit, A., Yaish, P., Gilon, C., et al.Tyrphostins I: Synthesis and biological activity of protein tyrosine kinase inhibitorsJ. Med. Chem.32(10),2344-2352(1989)
Sagara, Y., Ishige, K., Tsai, C., et al.Tyrphostins protect neuronal cells from oxidative stressJ. Biol. Chem.277(39),36204-36215(2002)