Pyrotinib dimaleate
Cat. No.:YN340052
产品名称: | Pyrotinib dimaleate |
CAS No.: | 1397922-61-0 |
Chemical Name: | |
Synonyms: | SHR-1258 dimaleate |
分子量: | 815.22 |
分子式: | C₄₀H₃₉ClN₆O₁₁ |
SMILES: | O=C(NC1=C(OCC)C=C2N=CC(C#N)=C(NC3=CC=C(OCC4=NC=CC=C4)C(Cl)=C3)C2=C1)/C=C/[C@@H]5N(C)CCC5.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Pyrotinib dimaleate (SHR-1258 dimaleate) 是有效、选择性的EGFR/HER2双重抑制剂,IC50值分别为 13 nM 和 38 nM。 |
IC50和靶点: | [{name:"HER2:38 nM (IC50)"},{name: "EGFR:13 nM (IC50)"}] |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |